Volume 2, Issue 1, March 2018, Page: 18-23
Plasmid Profile Analysis and Curing of Multidrug-Resistant Bacteria Isolated from Hospital Environmental Surfaces in Akure Metropolis, Ondo State, Nigeria
Anthony Kayode Onifade, Department of Microbiology, The Federal University of Technology, Akure, Nigeria
Ogedegbe Gloria Palmer, Department of Microbiology, The Federal University of Technology, Akure, Nigeria
Received: Apr. 19, 2018;       Accepted: May 2, 2018;       Published: May 24, 2018
DOI: 10.11648/j.ajist.20180201.13      View  751      Downloads  27
Abstract
Plasmid profile analysis and curing of multidrug-resistant bacteria isolated from hospital environment in Akure metropolis, Ondo State Nigeria were investigated. Staphylococcus aureus, Streptococcus pyogenes, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae and Bacillus cereus were the bacterial isolated in the course of the research. The result revealed that Staphylococcus aureus and Pseudomonas aeruginosa showed multiple antibiotics resistance. Staphylococcus aureus and Pseudomonas aeruginosa are rapidly increasing as multidrug resistant strains worldwide. The results of antibiotics sensitivity test on the microorganisms subjected to plasmid analysis indicated that they were more susceptible to antibiotics after the plasmid curing of the microorganisms. The results from this investigative study have shown that resistance in S. aureus and P. aeruginosa are plasmid based as a result of its loss after curing.
Keywords
Plasmid, Hospital, Environment, Multiple, Antibiotics
To cite this article
Anthony Kayode Onifade, Ogedegbe Gloria Palmer, Plasmid Profile Analysis and Curing of Multidrug-Resistant Bacteria Isolated from Hospital Environmental Surfaces in Akure Metropolis, Ondo State, Nigeria, American Journal of Information Science and Technology. Vol. 2, No. 1, 2018, pp. 18-23. doi: 10.11648/j.ajist.20180201.13
Copyright
Copyright © 2018 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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